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CosDNA > 化妆品、保养品成分查询分析 > Octinoxate
Octinoxate
(Octylmethoxy Cinnamate, Octyl Methoxycinnamate, Ethylhexyl methoxycinnamate, 2-Ethylhexyl 4-methoxycinnamate, 2-Ethylhexyl-p-methoxycinnamate, Parsol MCX, Escalol 557)
桂皮酸盐, 4-甲氧基肉桂酸-2-乙基己基酯, 甲氧基肉桂酸辛酯, 2-羟基-4-甲氧基二苯甲酮, 甲氧基肉桂酸乙基己酯

分子量:290
Cas No:5466-77-3
致粉刺刺激性来源
00Sage Advice

紫外线吸收剂,可以阻隔 UVB 290-320,为防晒成份,目前全世界被广为採用的化学防晒成份。卫生署限量10%。

防晒成份,油性化学性紫外线吸收剂,危险指数为 2/5(越高越不好)[1]。
[1] 张丽卿,『优质保养品选择策略』,联经出版社,2003/07/10。
注明出自 CosDNA,并提供连结 http://www.cosdna.com 方可引用本资料

修訂:2009-06-24
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skyline_612
  
2008-12-04 14:24
刺激性高吗?
最少可加多少%?
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skyline_612
  
2008-12-04 14:24
刺激性高吗?
最高可加多少%?
teco0726
  
2009-08-14 07:21 
最高只可到10% ,刺激性算低 ,

在防晒产品中很常见
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blueriver
  
2010-02-28 23:20
日文:
メトキシケイヒ酸エチルヘキシル、
メトキシケイヒ酸オクチル、
パラメトキシケイ皮酸2-エチルヘキシル,
参见:http://www.ba-m-bi.com/seibun/gaiyo/metokisi.htm
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alicelau
  
2010-06-06 19:54
对皮肤的刺激性小,但在动物试验中观察到其对雌激素有所影响,浓度限量10%。
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yixuan_126
  
2012-10-16 17:06
干扰正常内分泌。
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rs121
  
2013-06-06 13:05
请问它的危险体现在哪里
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yan1221
  
2014-01-15 16:01
Extensive research has shown that a number of UV filters frequently used in the formulation of commercial sunscreens, such as 4 MBC, octyl methoxycinnamate, oxybenzone (benzophenone-3), octyl-dimethyl-PABA and octinoxate, possess endocrine activity. Endocrine disruptors are chemicals that interfere with endogenous hormone action and/or production. These have been implicated in the development of a number of diseases in both males and females, including cancer of the mammary glands and reproductive organs, as well as the abnormal development of the male reproductive system. In one study, the application of three active ingredients commonly found in sunscreens (oxybenzone, 4-MBC and octinoxate) for one week led to a drop in testosterone and estradiol levels in men. More worrying is that these chemicals have been found in breast milk at concentrations known to have oestrogenic effects.
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sofiekk
  
2015-08-16 18:16
这个成分晚上涂了会堵塞毛孔吗?
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dreamivan69
  
2016-05-25 19:20
这个成分是皮肤炎的过敏原之一,不适合敏感肌用
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okaypore
  
2016-06-12 16:22
同关心,为什么这个长期危险性评分为6这么高?【我自己就长期使用这款产品....
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ruru
  
2016-06-24 14:46
桂皮酸盐(octinoxate)会导致男性体内睪固酮下降。
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ruru
  
2016-06-30 17:16
一个或多个人类病例研究表明可能有光敏性或过敏作用
一个或多个动物的研究表明在高剂量有发展的影响
一个或多个动物的研究表明在高剂量有生殖的影响
一个或多个动物的研究表明在高剂量有肝脏的影响
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mill0625
  
2016-09-23 14:10
不建议使用的物质
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helen114
  
2016-11-26 21:37
在安全浓度限量内使用安全?
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tomboy77
  
2016-12-22 14:25 
甲氧基肉桂酸辛酯 (Octinoxate)
作用是以吸收阳光中的中波紫外线(UVB),保护皮肤免于其伤害,是目前最常广泛使用的 UVB 防晒乳。甲氧基肉桂酸辛酯对皮肤刺激性小,但却会扰乱荷尔蒙、造成皮肤老化,并产生自由基破坏皮肤细胞。
http://news.everydayhealth.com.tw/2015/06/25/5773-%E8%81%B0%E6%98%8E%E6%8C%91%E9%81%B8%EF%BC%816%E7%A8%AE%E9%98%B2%E6%9B%AC%E4%B9%B3%E5%8D%B1%E9%9A%AA%E6%88%90%E5%88%86%E5%A4%A7%E5%89%96%E6%9E%90
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ju82831
  
2017-05-31 21:14
即便在低剂量的情况下,会刺激珊瑚的共生藻体内的病毒攻击共生藻,间接使珊瑚白化甚至死亡,而共生藻死亡后的病毒被释入海水后,导致周边海水病毒浓度增加,提高了其他珊瑚体内共生藻的感染率。

资料来源:环境资讯中心TEIA
bigmomo
  
2018-07-17 13:14
Regarding safety, there are also some concerns around Octinoxate. In vitro (made in the lab not on real people) and animal studies have shown that it may produce hormonal (estrogen-like) effects. Do not panic, the studies were not conducted under real life conditions on real human people, so it is probably over-cautious to avoid Octinoxate altogether. However, if you are pregnant or a small child (under 2 yrs. old), choose a physical (zinc oxide/titanium dioxide) or new-generation Tinosorb based sunscreen, just to be on the super-safe side. :)

Overall, Ethylhexyl Methoxycinnamate is an old-school chemical sunscreen agent. There are plenty of better options for sun protection today, but it is considered "safe as used" (and sunscreens are pretty well regulated) and it is available worldwide (can be used up to 10% in the EU and up to 7.5% in the US).
https://incidecoder.com/ingredients/ethylhexyl-methoxycinnamate
lilacKaZ
  
2019-04-16 18:44
https://www.medpartner.club/wp-content/uploads/2017/07/%E9%98%B2%E6%9B%AC%E7%B3%BB%E5%88%975_%E8%A1%A8%E6%A0%BC.png
lilacKaZ
  
2019-04-16 18:46
美的好朋友制作的表格
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